Granulomatous mycosis fungoides, a rare subtype of cutaneous T-cell lymphoma.

GMF: granulomatous mycosis fungoides INF-a: interferon alfa MF: mycosis fungoides TCR: T-cell receptor G ranulomatous mycosis fungoides (GMF) is an unusual histologic subtype of cutaneous T-cell lymphoma. The diagnosis of GMF is usually established after observation of a granulomatous inflammatory reaction associated with a malignant lymphoid infiltrate. Epidermotropism, a clue to diagnosis in classical mycosis fungoides (MF) may be absent in about 47% of cases of GMF. In some instances, the granulomatous component may be intense and obscures the lymphomatous component of the infiltrate. There are no distinctive clinical patterns associated with GMF.